September 14, 2021 Fargo South High School @ Fargo North High School Fargo North High School 3-0
September 14, 2021 Shanley High School @ Fargo Davies High School Davies High School 3-0
September 14, 2021 Grand Forks Central High School @ Grand Forks Red River Grand Forks Red River 3-1
September 14, 2021 West Fargo High School @ Devils Lake Firebirds Devils Lake High School 3-0
September 14, 2021 Valley City High School @ West Fargo Sheyenne High School